Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Asoxime dichloride (Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate) is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor, α7 nAChR. Asoxime dichloride (HI-6) can be used as an antigen and improves vaccination efficacy in the nervous system. Asoxime dichloride involves in modulating immunity response.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 53.00 | |
10 mg | In stock | $ 84.00 |
Description | Asoxime dichloride (Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate) is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor, α7 nAChR. Asoxime dichloride (HI-6) can be used as an antigen and improves vaccination efficacy in the nervous system. Asoxime dichloride involves in modulating immunity response. |
In vivo | A combination of HI-6 and keyhole limpet hemocyanin (KLH) produces a vaccination of almost the same efficacy as that for Freund's complete adjuvant[1]. Asoxime dichloride (intramuscular injection into the rear limb; 2% and 0.2% of median lethal dose 15.6 and 1.56 mg/kg; 21 or 65 days) significantly improved vaccination efficacy as a dose-dependent manner when KLH is 1 mg/kg[1]. |
Synonyms | Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate, Asoxime (dichloride), HI-6 |
Molecular Weight | 359.21 |
Formula | C14H16Cl2N4O3 |
CAS No. | 34433-31-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 10 mg/mL (27.8 mM)
You can also refer to dose conversion for different animals. More
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Asoxime dichloride 34433-31-3 Neuroscience AChR Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate HI6 HI 6 Asoxime Asoxime Dichloride Asoxime (dichloride) HI-6 inhibitor inhibit