Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Amino-PEG4-(CH2)3CO2H is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Description | Amino-PEG4-(CH2)3CO2H is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 279.33 |
Formula | C12H25NO6 |
CAS No. | 144598-03-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Amino-PEG4-(CH2)3CO2H 144598-03-8 Others Amino-PEG-4-(CH2)3CO2H AminoPEG4(CH2)3CO2H Amino PEG4 (CH2)3CO2H inhibitor inhibit