store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Aligeron is a non-selective prostaglandin (PG) antagonist that inhibits PGF2α- and PGE2-induced decreases in blood pressure in cats, and can be used to inhibit PGF2α-induced diarrhea in mice and PGE2-induced paw edema in rats.Aligeron is known to have an antioxidant-protective effect against vascular complications.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 700.00 | |
5 mg | In stock | $ 1,800.00 |
Description | Aligeron is a non-selective prostaglandin (PG) antagonist that inhibits PGF2α- and PGE2-induced decreases in blood pressure in cats, and can be used to inhibit PGF2α-induced diarrhea in mice and PGE2-induced paw edema in rats.Aligeron is known to have an antioxidant-protective effect against vascular complications. |
In vitro |
Aligeron demonstrates a wide-ranging spectrum of antagonistic activity against various spasmogens in diverse isolated organs. In experiments conducted on the isolated perfused rabbit artery, the antagonistic effects of Aligeron against the vasoconstrictor impacts of noradrenaline and adrenaline are evident.[1]] The effect of Aligeronin in vitro lacks selectivity and is probably due to interference with the action of Ca2+.[3] |
In vivo | Aligeron(5 mg/kg; i.v.) increases cortical resistance to hypoxia and accelerates the recovery of cortical bioelectrical activity In hypoventilation hypoxia. Aligerons show a protective effect in KCl- and AMP-induced depressions manifested, And show a decrease in the degree and duration of the depression.[2] |
Molecular Weight | 292.42 |
Formula | C20H24N2 |
CAS No. | 70713-45-0 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
You can also refer to dose conversion for different animals. More
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Aligeron 70713-45-0 GPCR/G Protein Immunology/Inflammation Prostaglandin Receptor inhibitor inhibit