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AZD1940

Catalog No. T30252 CAS 881413-29-2

Synonyms: UNII-0J0035E9FT, AZD-1940, AZD 1940

AZD1940 is a high affinity CB(1)/CB(2) receptor agonist of the cannabinoid with oral activity. Application in the study of orofacial pain.

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AZD1940, CAS 881413-29-2

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	AZD1940 is a high affinity CB(1)/CB(2) receptor agonist of the cannabinoid with oral activity. Application in the study of orofacial pain.
In vitro	AZD1940 binds with high affinity to human, rat and mouse CB1 and CB2 receptors and displays full agonism at both receptors in all three species[1].
In vivo	After given orally to human, the mean maximum plasma concentration (Cmax) for AZD1940 800 mg was 9.3 nmol/L . The mean concentration over post-dose eight hours for AZD1940 was 236 nmol.h/L[1].

Synonyms	UNII-0J0035E9FT, AZD-1940, AZD 1940
Molecular Weight	413.53
Formula	C20H29F2N3O2S
CAS No.	881413-29-2

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 90.0 mg/mL (217.6 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Schou M, et al. Radiolabeling of the cannabinoid receptor agonist AZD1940 with carbon-11 and PET microdosing in non-human primate. Nucl Med Biol. 2013 Apr;40(3):410-4. 2. Kalliomäki J, et al. Evaluation of the analgesic efficacy and psychoactive effects of AZD1940, a novel peripherally acting cannabinoid agonist, in human capsaicin-induced pain and hyperalgesia. Clin Exp Pharmacol Physiol. 2013 Mar;40(3):212-8. 3. Grossman S, et al. Cannabis and orofacial pain: a systematic review. Br J Oral Maxillofac Surg. 2022 Jun;60(5):e677-e690.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

AZD1940 881413-29-2 GPCR/G Protein Cannabinoid Receptor UNII-0J0035E9FT AZD-1940 AZD 1940 Inhibitor inhibitor inhibit

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