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ACTH 11-24 acetate(4237-93-8 free base)

Catalog No. TP1248L CAS 79190-56-0

Synonyms: Adrenocorticotropic Hormone (11-24) acetate

ACTH (11-24) acetate is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH (1-39) and ACTH (1-10) in isolated adrenal cells.

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ACTH 11-24 acetate(4237-93-8 free base), CAS 79190-56-0

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	ACTH (11-24) acetate is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH (1-39) and ACTH (1-10) in isolated adrenal cells.
In vitro	ACTH (11-24) acts as an antagonist of adrenocorticotropic hormone receptor[1]. ACTH (11-24) induces cortisol secretion submaximally in freshly dispersed or cultured beef adrenal cortical cells. The maximal cortisol release by ACTH (11-24) is enhanced by forskolin but inhibited by calcium channel blockers[2].
In vivo	ACTH (11-24) blocks electroacupuncture (EA) anti-edema but not EA anti-hyperalgesia in rats[1].

Synonyms	Adrenocorticotropic Hormone (11-24) acetate
Molecular Weight	1712.12
Formula	C79H138N24O18
CAS No.	79190-56-0

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: Insoluble

H2O: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Li ZG, et al. Adrenocorticotropin(1-10) and -(11-24) promote adrenal steroidogenesis by different mechanisms. Endocrinology. 1989 Aug;125(2):592-6.

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Keywords

ACTH 11-24 acetate(4237-93-8 free base) 79190-56-0 GPCR/G Protein Neuroscience Melanocortin Receptor Adrenocorticotropic Hormone (11-24) acetate ACTH 11 24 acetate(4237 93 8 free base) ACTH 1124 acetate(4237938 free base) Inhibitor inhibitor inhibit

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