0-4℃ for short term (days to weeks), or -20℃ for long term (months).
4-Aminobutyric acid is the most common inhibitory neurotransmitter in the central nervous system.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | 38.00 | |
100 mg | In stock | 50.00 | |
200 mg | In stock | 65.00 | |
500 mg | In stock | 104.00 |
Description | 4-Aminobutyric acid is the most common inhibitory neurotransmitter in the central nervous system. |
Targets&IC50 | GABA, |
Cell Research |
GABRP-positive cell lines, KLM-1 and PK-45P, and GABRP-negative cell lines, PK-59 and KP-1N, are incubated with GABA or GABA receptor agonist Muscimol at serial concentration (0, 1, 10, 100 μmol/L) in appropriate medium supplemented with 1% FBS for 6 days. To inhibit the GABA-mediated pathway, cells are incubated with 250 μmol/L of GABAA receptor antagonist bicuculline methiodide or 1 mmol/L of GABAB receptor antagonist CGP-35348. After 6 days of exposure to either of these drugs, cell viability is measured by MTT assay as described above.(Only for Reference)
Cell lines: PDAC cell lines KLM-1, SUIT-2, KP-1N, PK-1, PK-45P, and PK-59
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Animal Research |
Animal Model: Mice(CD1 mice) with STZ-induced diabetes
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Synonyms | γ-Aminobutyric acid , 4-Aminobutanoic acid , GABA , Gamma-aminobutyric acid , Piperidic acid |
Purity | 98.00% |
Molecular Weight | 103.12 |
Formula | C4H9NO2 |
CAS No. | 56-12-2 |
0-4℃ for short term (days to weeks), or -20℃ for long term (months).
H2O: 50 mg/mL (484.87 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
Safe and effective drug dosing is necessary, regardless of its purpose of administration. Learn More
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Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.