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4-Aminobutyric acid

Catalog No. T0508 CAS 56-12-2

Synonyms: γ-Aminobutyric acid, 4-Aminobutanoic acid, GABA, Gamma-aminobutyric acid, Piperidic acid

4-Aminobutyric acid is the most common inhibitory neurotransmitter in the central nervous system.

4-Aminobutyric acid, CAS 56-12-2

Pack Size	Availability	Price/USD
50 mg	In stock	38.00
100 mg	In stock	50.00
200 mg	In stock	65.00
500 mg	In stock	104.00

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Purity 98.00%

HNMR COA

Datasheet SDS

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Storage & Solubility Information

Description	4-Aminobutyric acid is the most common inhibitory neurotransmitter in the central nervous system.
Targets&IC50	GABA
Cell Research	GABRP-positive cell lines, KLM-1 and PK-45P, and GABRP-negative cell lines, PK-59 and KP-1N, are incubated with GABA or GABA receptor agonist Muscimol at serial concentration (0, 1, 10, 100 μmol/L) in appropriate medium supplemented with 1% FBS for 6 days. To inhibit the GABA-mediated pathway, cells are incubated with 250 μmol/L of GABAA receptor antagonist bicuculline methiodide or 1 mmol/L of GABAB receptor antagonist CGP-35348. After 6 days of exposure to either of these drugs, cell viability is measured by MTT assay as described above.(Only for Reference) Cell lines: PDAC cell lines KLM-1, SUIT-2, KP-1N, PK-1, PK-45P, and PK-59

Synonyms	γ-Aminobutyric acid , 4-Aminobutanoic acid , GABA , Gamma-aminobutyric acid , Piperidic acid
Purity	98.00%
Molecular Weight	103.12
Formula	C4H9NO2
CAS No.	56-12-2

Storage

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

Solubility Information

Water: 10 mM

DMSO: Insoluble

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Takehara A, et al. Cancer Res. 2007, 67(20):9704-12. 2. Soltani N, et al. Proc Natl Acad Sci U S A. 2011, 108(28):11692-7. 3. Bhat R, et al. Proc Natl Acad Sci U S A. 2010, 107(6):2580-5.

Related compound libraries

This product is contained In the following compound libraries：

Approved Drug Library Bioactive Compound Library Inhibitor Library Natural Compound Library for HTS Anti-cancer Compound Library Clinical Compound Library Anti-diabetic Compound Library Neuronal Signaling Compound Library Human Endogenous Metabolite Compound Library Ion Channel Inhibitor Library Immunology/Inflammation Compound Library GPCR Compound Library Anti-cancer Approved drug Library Anti-cancer Clinical Compound Library Anti-Metabolism Disease Compound Library Anti-obesity Compound Library Antitumor Natural Products Library Anti-cancer Drug library Drug Repurposing Library Neurotransmitter Receptor Compound Library Neurodegenerative disease-related Compound Library FDA Approved & Pharmacopeial Drug Library Anti-Alzheimer's Disease Compound Library Gut Microbial Metabolite Library

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Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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