store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1-Cinnamoylpyrrolidine, a natural product prepared from Piper caninum, can be used as a DNA strand breaking agent, inducing the relaxation of the plasmid pBR322 DNA superhelix in the presence of Cu2+. 1-Cinnamoylpyrrolidine inhibits PAF-induced platelet aggregation with an IC50 value of 37.3 μM. value was 37.3 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 115.00 | |
5 mg | In stock | $ 279.00 | |
10 mg | In stock | $ 413.00 | |
25 mg | In stock | $ 688.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 397.00 |
Description | 1-Cinnamoylpyrrolidine, a natural product prepared from Piper caninum, can be used as a DNA strand breaking agent, inducing the relaxation of the plasmid pBR322 DNA superhelix in the presence of Cu2+. 1-Cinnamoylpyrrolidine inhibits PAF-induced platelet aggregation with an IC50 value of 37.3 μM. value was 37.3 μM. |
Targets&IC50 | 1-Cinnamoylpyrrolidine:37.3 μM (IC50) |
In vitro | In a survey of the active components of crude plant extracts for their ability to cleave DNA, a crude extract prepared from Piper caninum was found to induce the relaxation of supercoiled pBR322 plasmid DNA in the presence of Cu(2+). Bioassay-guided fractionation was carried out on this extract, guided by an in vitro DNA strand scission assay. Three active principles were isolated and identified as N-cis-feruloyl tyramine (1),N-trans-feruloyl tyramine (2), and 1-cinnamoylpyrrolidine (3). Compounds 1-3 represent a structurally new type of DNA strand scission agent.[1] |
Molecular Weight | 201.26 |
Formula | C13H15NO |
CAS No. | 52438-21-8 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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1-Cinnamoylpyrrolidine 52438-21-8 Others Platelet aggregation 1 Cinnamoylpyrrolidine 1Cinnamoylpyrrolidine inhibitor inhibit