Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(R)-Elagolix (NBI-56418) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full suppression at higher doses.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 32.00 | |
2 mg | In stock | $ 45.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 113.00 | |
25 mg | In stock | $ 198.00 | |
50 mg | In stock | $ 347.00 | |
100 mg | In stock | $ 513.00 | |
200 mg | In stock | $ 732.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 97.00 |
Description | (R)-Elagolix (NBI-56418) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full suppression at higher doses. |
Targets&IC50 | GnRHR: Ki : 3.7 nM, GnRHR:0.25 nM |
Synonyms | NBI-56418 |
Molecular Weight | 631.59 |
Formula | C32H30F5N3O5 |
CAS No. | 834153-87-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (158.33 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
(R)-Elagolix 834153-87-6 GPCR/G Protein GNRH Receptor Inhibitor GnRH Receptor NBI-56418 (R) Elagolix GNRHR Gonadotropin releasing hormone receptor Elagolix NBI 56418 NBI56418 inhibit (R)Elagolix inhibitor