Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)17-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. At a concentration of 2 μM the (S)-enantiomer of 17-HETE inhibits proximal tubule ATPase activity by as much as 70%, whereas the (R)-isomer is inactive.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 μg | 35 days | $ 365.00 | |
50 μg | 35 days | $ 695.00 | |
100 μg | 35 days | $ 1,310.00 |
Description | Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)17-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. At a concentration of 2 μM the (S)-enantiomer of 17-HETE inhibits proximal tubule ATPase activity by as much as 70%, whereas the (R)-isomer is inactive. |
Molecular Weight | 320.473 |
Formula | C20H32O3 |
CAS No. | 128914-47-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PBS (pH 7.2): 0.8 mg/mL
Ethanol: Miscible
DMSO: Miscible
0.1 m Na2CO3: 2 mg/mL
DMF: Miscible
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(±)17-HETE 128914-47-6 (±)17 HETE 17-HETE (±)17HETE inhibitor inhibit