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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T80697 | β5i-IN-1 | Proteasome | |
β5i-IN-1 is a selective inhibitor of β5i, exhibiting potent activity with an IC50 of 8.463 nM. It modulates immune responses by promoting the release of TNF-α and IL-6 and affecting NF-κB transcriptional activity. This c... | |||
T37420 | Ac-ANW-AMC | Ac-ANW-AMC,Ac-Ala-Asn-Trp-AMC | |
Ac-ANW-AMC is a fluorogenic substrate for the β5i/LMP7 subunit of the 20S immunoproteasome. [1] Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify the activity of the β... | |||
T82529 | DPLG3 | ||
DPLG3, a specific inhibitor of the chymotryptic-like β5i subunits, effectively inhibits mouse i-20S proteasomes with an IC50 value of 9.4 nM. This compound has applications in the research of immune diseases [1]. |