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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T81115 | sPLA2-IIA Inhibitor | ||
The sPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK, specifically cyclic 2-Nal-Leu-Ser-2-Nal-Arg (c2), which interacts with human IIA phospholipase A2 (hGIIA) to impede its ester bond hydrolyzing function. A... | |||
T2044 | Varespladib | LY315920 | Phospholipase |
Varespladib (LY315920), a specific and effective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor(IC50=7 nM), has been investigated for the treatment and prevention of sickle cell disease, vaso-occlusiv... | |||
T27731 | sPLA2 inhibitor 1 | KH-064,KH 064,KH064,5-BPP acid | |
KH064 is a sPLA2-IIA inhibitor of oral activity. | |||
T12990 | sPLA2-X Inhibitor 31 | Others | |
sPLA2-X Inhibitor 31 is a selective inhibitor of secreted phospholipase A2 type X (sPLA2-X) (IC50s of 26 nM, 310 nM, and 2230 nM for sPLA2-X, sPLA2-IIa, and sPLA2-V, respectively). | |||
T30831 | Cgp 43182 | Cgp-43182,Cgp43182 | |
CGP 43182 is an effective inhibitor of group IIA secretory phospholipase A2 (Group IIA sPLA2) activity in vitro, which can be used to prevent the synergistic effect of pro-inflammatory genes stimulated by cytokines media... | |||
T39173 | Varespladib sodium | LY315920 sodium | |
Varespladib sodium (LY315920 sodium) is a highly potent and selective inhibitor of group IIA secretory phospholipase A2 (sPLA2), with an IC50 of 9 nM. It demonstrates significant inhibitory activity against sPLA2 in seru... |