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Search Results for " mantle "

5

Compounds

Cat No. Product Name Synonyms Targets
T2558 Cladribine 2-chlorodeoxyadenosine,2-Chloro-2′-deoxyadenosine,CldAdo,2CdA Apoptosis , Adenosine deaminase
Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.
T60706 LP-284
LP-284 kills solid tumours. LP-284 is a potent DNA alkylating agent that can be used in the hematologic cancers studies with compromised DNA repair, for example, mantle cell lymphoma (MCL) [1] [2].
T36981 GSK 591 dihydrochloride
Potent and selective PRMT5 inhibitor (IC50 = 4 nM). Selective for PRMT5 over a panel of other PRMTs and lysine methyltransferases. Inhibits proliferation of mantle cell lymphoma (MCL) in vitro. To request the negative...
T70741 AZ-TAK1
AZ-Tak1 is a potent and a relatively selective inhibitor of TAK1 kinase activity, with an IC50 of 0.009 mM. AZ-Tak1 treatment decreased the level of p38 and ERK in mantle cell lymphoma cells, and induced apoptosis in a d...
T35481 DD 03-171
Potent and selective BTK Degrader (IC50 = 5.1 nM); degrades BTK in a proteasome- and CRBN-dependent manner. Suppresses BTK signaling and proliferation in mantle cell lymphoma (MCL) cells by degrading BTK, IKFZ1, and IKFZ...
TargetMol