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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0881 | 6-Aminocaproic acid | EACA,6-Aminohexanoic acid,Epsilon-Amino-n-caproic Acid,(6-)ε-Aminocaproic acid | Others |
6-Aminocaproic acid (EACA) is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties. | |||
T0949 | Tranexamic acid | Amstat,Tranexamsaeure | Others |
Tranexamic acid (Amstat) is an Antifibrinolytic Agent. The physiologic effect of tranexamic acid is by means of Decreased Fibrinolysis. | |||
T70118 | PSI-112 | ||
PSI-112 is a fibrinolysis inhibitor. | |||
T28842 | SQ-24,798 | SQ 24,798,SQ24,798 | |
SQ-24,798 is an inhibitor of the thrombin-activatable fibrinolysis and carboxypeptidase N (CPN). | |||
T70652 | SAR-104772 | ||
SAR-104772 is a novel inhibitor of TAFIa (activated thrombin-activatable fibrinolysis inhibitor). | |||
T71129 | AZD6564 | ||
AZD6564 is a fibrinolysis inhibitor which acts via interference of a protein-protein interaction. | |||
T39551 | S62798 | S62798 | |
S62798 is a highly potent and selective compound that inhibits activated thrombin activatable fibrinolysis inhibitor (TAFIa) with an IC50 value of 6 mM. | |||
T11100 | DS-1040 Tosylate | Others | |
DS-1040 Tosylate is an oral active, selective thrombolytic inhibitor with IC50s of 5.92 nM and 8.01 nM for human and rat TAFIa, is an orally active, selective inhibitor of activated thrombin-activatable fibrinolysis inhi... | |||
T71851 | 5-trans-Prostaglandin E2 | ||
5-trans-Prostaglandin E2 accelerates fibrinolysis by enhancing plasminogen activation mediated by tissue-type plasminogen activator. It also inhibits platelet aggregation in human PRP. | |||
T82286 | Glycylglycylcysteine | ||
Glycylglycylcysteine is an inhibitor of Thrombin Activatable Fibrinolysis Inhibitor (TAFI), exhibiting a K_i value of 0.99 µM and an IC_50 of 9.4 µM in TAFI substrate assays. TAFI, a basic carboxypeptidase, hinders fibri... | |||
T82526 | Drotrecogin alfa (activated) | ||
Drotrecogin alfa (activated) (DrotAA), a recombinant human activated protein C (APC), mitigates smoke-induced elevations in pulmonary microvascular permeability and proinflammatory cytokine IL-1β levels in rats. It also ... | |||
T72113 | 6-Aminocaproic acid hydrochloride | EACA hydrochloride,EACA hydrochloride ; Epsilon-Amino-n-caproic Acid hydrochloride ; 6-Aminohexanoic acid hydrochloride,6-Aminohexanoic acid hydrochloride,Epsilon-Amino-n-caproic Acid hydrochloride | |
6-Aminocaproic acid hydrochloride, a monoamino carboxylic acid derivative, serves as a potent, orally active antifibrinolytic agent by inhibiting plasmin and plasminogen. It functions through competitive binding to lysin... |