2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5420 | Cycloguanil hydrochloride | Chloroguanide Triazine | Parasite , Drug Metabolite |
Cycloguanil hydrochloride (Chloroguanide Triazine) is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms, r... | |||
T22409 | Proguanil | chloroguanide,chlorguanide | Others |
Proguanil, a prophylactic antimalarial drug, inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of pyrimidines and purines, which are essential for DNA synthesis and cell multiplication... |