antimalarial — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10336	Antimalarial agent 1		Parasite
	Antimalarial agent 1 is an effective antimalarial agent.		Parasite
T9984	Antimalarial agent 13	N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine	Parasite
	Antimalarial agent 13 (N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine) is a potent antimalarial agent.		Parasite
T22381	Antimalarial agent 14	4-hydroxy-3-phenyl-naphthalene-1,2-dione,2-Hydroxy-3-phenyl-1,4-naphthoquinone	Others
	Antimalarial agent 14 (NSC-102533) is a bioactive chemical.		Others
T79535	Antimalarial agent 30		Parasite
	Antimalarial agent 30 has anti-Plasmodium berghei liver stage parasite activity and antimalarial activity for the study of malarial infections.		Parasite
T61200	Antimalarial agent 3
	Antimalarial agent 3, an antimalarial agent, exhibits potent activity against Plasmodium with an IC50 of 0.035 μM. Furthermore, it demonstrates an exceptionally high selectivity index in relation to mammalian cells.
T63456	Antimalarial agent 12
	Antimalarial agent 12 is an effective antimalarial agent that inhibits the growth of Plasmodium falciparum strains Dd2 and 3D7 with EC50 values of 155 nM and 136 nM, respectively. antimalarial agent 12 has a MIC >250,000...
T63052	Antimalarial agent 10
	Antimalarial agent 10 (Compound 17b) is an amino alcohol-quinoline compound. Antimalarial agent 10 is also an antimalarial agent capable of acting on Pf3D7 (IC50: 14.9 nM) and PfW2 (IC50: 11 nM) with a selectivity index ...
T63413	Antimalarial agent 15
	Antimalarial agent 15 is a parasite inhibitor that exhibits antimalarial effects and inhibits the growth of Plasmodium falciparum 3D7 with an IC50 value of 20 nM.
T74695	Antimalarial agent 17
	Antimalarial agent 17, functioning both as an antimalarial agent and a herbicide, inhibits photosystem II and demonstrates post-emergence herbicidal efficacy comparable to commercial herbicides [1].
T83044	Antimalarial agent 33		Parasite
	Antimalarial agent 33 (compound 5g) exhibits antiplasmodial activity targeting both erythrocytic and hepatic stages of Plasmodium, with an effective concentration (EC50) of 1.1 μM against the K1 strain of P. falciparum. ...		Parasite
T79460	Antimalarial agent 28		Parasite
	Antimalarial agent 28 (Compound 2i) acts as an antiplasmodial agent, exhibiting inhibition of P. berghei with IC50 values of 0.561 μM for the liver stage, 0.14 μM for early gametocytes, and 4.34 μM for the ring stages of...		Parasite
T78936	Antimalarial agent 27		Parasite
	Antimalarial agent 27 (compound 11a) potently inhibits P. falciparum with an IC50 of 0.37 μM and targets the parasite's 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) enzyme with an IC50 of 0.11 μM, indicating its...		Parasite
T63043	Antimalarial agent 2
	Antimalarial agent 2 is an orally active, novel antimalarial agent that exhibits rapid in vitro killing effects.
T72396	Antimalarial agent 20
	Antimalarial agent 20, exhibiting potent efficacy with an IC50 value of 0.6 nM against the P. falciparum NF54 parasite strain within the NF54 albumax assay, serves as a significant antimalarial compound.
T62936	Antimalarial agent 8
	Antimalarial agent 8 (Compound 7e) is a novel, orally active antimalarial agent that is effective against P. falciparum in vitro and effective orally in an in vivo mouse model of malaria (40 mg/kg).
T78952	Antimalarial agent 26		Parasite
	Antimalarial agent 26, a derivative of 1,4-naphthoquinones, demonstrates antimalarial properties through oral administration. It exhibits cytotoxic effects on P. falciparum while maintaining selectivity against mammalian...		Parasite
T72416	Antimalarial agent 18
	Antimalarial agent 18, a powerful antimalarial compound characterized by its electronic, highly lipophilic, and siderophoric properties, falls within the acyloxymethyl series, acting as a fosmidomycin surrogate. It effec...
T62300	Antimalarial agent 11
	Antimalarial agent 11 (compound 1) is a potent antimalarial agent, a spirocyclic chromane. Antimalarial agent 11 is able to act on D6 (EC50: 1.48 μM) and ARC08-022 (EC50: 1.81 μM).
T63655	Antimalarial agent 9
	Antimalarial agent 9 is an effective antimalarial agent, a quinoline-imidazole derivative compound. antimalarial agent 9 showed significant in vitro antimalarial effects against CQ-susceptible strains (IC50-0.14 μM) and ...
T62537	Antimalarial agent 7
	Antimalarial agent 7 is a potent and effective inhibitor of PfATP4. Antimalarial agent 7 has potential for the study of the human plasmodium falciparum.