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Search Results for " anti-cd47 "

6

Compounds

Cat No. Product Name Synonyms Targets
T35390 Magrolimab Hu5F9-G4,Magrolimab (anti-CD47) Others
Magrolimab (Hu5F9-G4) is a humanized anti-CD47 IgG4 monoclonal antibody that exhibits its antitumor activity by blocking CD47 and binds primarily to the N-terminal pyroglutamate of CD47, and can be used in combination wi...
T78246 Lemzoparlimab TJC4,TJ011133
Lemzoparlimab (TJ011133; TJC4), a humanized anti-CD47 IgG4 antibody, exhibits potent antitumor activity [1].
T76732 CC-90002
CC-90002, a humanized anti-CD47 monoclonal antibody (mAb), demonstrates high affinity for CD47, characterized by a subnanomolar dissociation constant (K d). It is utilized in the research of hematologic malignancies and ...
T77065 Ligufalimab
Ligufalimab (AK 117), a humanized IgG4 monoclonal antibody targeting CD47, does not lead to red blood cell (RBC) hemagglutination but promotes phagocytosis and exhibits anti-tumor activity [1].
T78276 KWAR 23
KWAR23, an anti-human SIRPα antibody, exhibits high-affinity binding to human SIRPα, inhibiting its interaction with CD47. Demonstrating antitumor activity, KWAR23 is efficacious in conjunction with tumor-opsonizing anti...
T82994 Anzurstobart BMS-986351,CC-95251
Anzurstobart (CC-95251; BMS-986351), a fully human monoclonal anti-SIRPα antibody with high affinity, inhibits CD47-SIRPα interaction. It potentiates macrophage-mediated phagocytosis of DLBCL cell lines in co-culture ass...
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