6
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35390 | Magrolimab | Hu5F9-G4,Magrolimab (anti-CD47) | Others |
Magrolimab (Hu5F9-G4) is a humanized anti-CD47 IgG4 monoclonal antibody that exhibits its antitumor activity by blocking CD47 and binds primarily to the N-terminal pyroglutamate of CD47, and can be used in combination wi... | |||
T78246 | Lemzoparlimab | TJC4,TJ011133 | |
Lemzoparlimab (TJ011133; TJC4), a humanized anti-CD47 IgG4 antibody, exhibits potent antitumor activity [1]. | |||
T76732 | CC-90002 | ||
CC-90002, a humanized anti-CD47 monoclonal antibody (mAb), demonstrates high affinity for CD47, characterized by a subnanomolar dissociation constant (K d). It is utilized in the research of hematologic malignancies and ... | |||
T77065 | Ligufalimab | ||
Ligufalimab (AK 117), a humanized IgG4 monoclonal antibody targeting CD47, does not lead to red blood cell (RBC) hemagglutination but promotes phagocytosis and exhibits anti-tumor activity [1]. | |||
T78276 | KWAR 23 | ||
KWAR23, an anti-human SIRPα antibody, exhibits high-affinity binding to human SIRPα, inhibiting its interaction with CD47. Demonstrating antitumor activity, KWAR23 is efficacious in conjunction with tumor-opsonizing anti... | |||
T82994 | Anzurstobart | BMS-986351,CC-95251 | |
Anzurstobart (CC-95251; BMS-986351), a fully human monoclonal anti-SIRPα antibody with high affinity, inhibits CD47-SIRPα interaction. It potentiates macrophage-mediated phagocytosis of DLBCL cell lines in co-culture ass... |