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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T82260 | Grisnilimab | WT1 | |
"Grisnilimab (WT1), an IgG2a monoclonal antibody targeting CD7, acts as a tumor suppressor in the pathogenesis of Wilms' tumor. It modulates the transcription of various genes and may be involved in post-transcriptional ... | |||
T82259 | Grisnilimab setaritox | WT1-RTA | |
Grisnilimab setaritox (WT1-RTA), an anti-CD7 antihuman T cell antibody linked to ricin A chain (RTA), exhibits in vitro cytotoxicity against CEM (T-lymphoblastic leukemia) cells with an ID 50 of 53 pM. The 30-kDa RTA com... | |||
TP2478 | WT-1 A1 | Tyr-Met-Phe-Pro-agn-Ala-Pro-Tyr-Leu | |
WT-1 A1 is an attractive target for immunotherapy in patients with pancreatic adenocarcinoma. | |||
T81328 | Quazomotide | ||
Quazomotide, a class II peptide epitope of WT1 with the sequence RSDELVRHHNMHQRNMTKL, elicits a peptide-specific CD4(+) response to target WT1(+) tumor cells. It serves both as an immunological agent for active immunizat... |