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Search Results for " wt1 "

4

Compounds

8

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T82260 Grisnilimab WT1
"Grisnilimab (WT1), an IgG2a monoclonal antibody targeting CD7, acts as a tumor suppressor in the pathogenesis of Wilms' tumor. It modulates the transcription of various genes and may be involved in post-transcriptional ...
T82259 Grisnilimab setaritox WT1-RTA
Grisnilimab setaritox (WT1-RTA), an anti-CD7 antihuman T cell antibody linked to ricin A chain (RTA), exhibits in vitro cytotoxicity against CEM (T-lymphoblastic leukemia) cells with an ID 50 of 53 pM. The 30-kDa RTA com...
TP2478 WT-1 A1 Tyr-Met-Phe-Pro-agn-Ala-Pro-Tyr-Leu
WT-1 A1 is an attractive target for immunotherapy in patients with pancreatic adenocarcinoma.
T81328 Quazomotide
Quazomotide, a class II peptide epitope of WT1 with the sequence RSDELVRHHNMHQRNMTKL, elicits a peptide-specific CD4(+) response to target WT1(+) tumor cells. It serves both as an immunological agent for active immunizat...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPK-01554 HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en...
TMPH-02312 Wilms tumor protein/WT1 Protein, Human, Recombinant (His & SUMO) Human E. coli
Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO....
TMPK-01549 HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en...
TMPK-01548 HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en...
TMPK-01523 Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi) Human & Mouse HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en...
TMPK-01522 Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi) Human & Mouse HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en...
TMPY-00140 ABP1/AOC1 Protein, Human, Recombinant (His) Human HEK293 Cells
Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putres...
TMPY-02402 WTAP Protein, Human, Recombinant (GST) Human E. coli
Wilms' tumor 1-associating protein (WTAP) was previously identified as a protein associated with Wilms' tumor-1 (WT-1) protein that is essential for the development of the genitourinary system. WT1 was originally identif...
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