4
8
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T82260 | Grisnilimab | WT1 | |
"Grisnilimab (WT1), an IgG2a monoclonal antibody targeting CD7, acts as a tumor suppressor in the pathogenesis of Wilms' tumor. It modulates the transcription of various genes and may be involved in post-transcriptional ... | |||
T82259 | Grisnilimab setaritox | WT1-RTA | |
Grisnilimab setaritox (WT1-RTA), an anti-CD7 antihuman T cell antibody linked to ricin A chain (RTA), exhibits in vitro cytotoxicity against CEM (T-lymphoblastic leukemia) cells with an ID 50 of 53 pM. The 30-kDa RTA com... | |||
TP2478 | WT-1 A1 | Tyr-Met-Phe-Pro-agn-Ala-Pro-Tyr-Leu | |
WT-1 A1 is an attractive target for immunotherapy in patients with pancreatic adenocarcinoma. | |||
T81328 | Quazomotide | ||
Quazomotide, a class II peptide epitope of WT1 with the sequence RSDELVRHHNMHQRNMTKL, elicits a peptide-specific CD4(+) response to target WT1(+) tumor cells. It serves both as an immunological agent for active immunizat... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-01554 | HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en... | |||
TMPH-02312 | Wilms tumor protein/WT1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO.... | |||
TMPK-01549 | HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en... | |||
TMPK-01548 | HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en... | |||
TMPK-01523 | Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi) | Human & Mouse | HEK293 Cells |
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en... | |||
TMPK-01522 | Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi) | Human & Mouse | HEK293 Cells |
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en... | |||
TMPY-00140 | ABP1/AOC1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putres... | |||
TMPY-02402 | WTAP Protein, Human, Recombinant (GST) | Human | E. coli |
Wilms' tumor 1-associating protein (WTAP) was previously identified as a protein associated with Wilms' tumor-1 (WT-1) protein that is essential for the development of the genitourinary system. WT1 was originally identif... |