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Search Results for " val-cit-pab-mmae "

18

Compounds

Cat No. Product Name Synonyms Targets
T18867 Val-Cit-PAB-MMAE
Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE . MMAE a potent mitotic inhibitor by inhibiting tubulin polymerizat...
T17983 Fmoc-Val-Cit-PAB-MMAE Others
Fmoc-Val-Cit-PAB-MMAE is consisted of the ADCs linker (Fmoc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE). Fmoc-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC.
T39307 Azido-PEG4-Val-Cit-PAB-MMAE Azido-PEG4-Val-Cit-PAB-MMAE
Azido-PEG4-Val-Cit-PAB-MMAE is a drug-linker conjugate for antibody-drug conjugates (ADCs), comprising the anti-mitotic agent monomethyl auristatin E (MMAE, a tubulin inhibitor), connected through the cleavable linker Az...
T39328 SuO-Glu-Val-Cit-PAB-MMAE
SuO-Glu-Val-Cit-PAB-MMAE is a chemical compound comprising a cleavable ADC linker, SuO-Glu-Val-Cit-PAB, and a potent tubulin inhibitor known as MMAE. It is utilized in the synthesis of antibody-drug conjugates (ADCs).
T77876 Py-MAA-Val-Cit-PAB-MMAE AAJ8D6-PY-Val-Cit-MMAE
Py-MAA-Val-Cit-PAB-MMAE (AAJ8D6-PY-Val-Cit-MMAE) serves as an ADC linker for Zapadcine-3a, a broad-spectrum anti-TRAILR2 ADC with antineoplastic properties. By targeting TRAILR2, Zapadcine-3a is internalized into the lys...
T18736 SuO-Val-Cit-PAB-MMAE Others
SuO-Val-Cit-PAB-MMAE is an ADC (antibody-drug conjugate) linker comprising the anti-mitotic monomethyl auristatin E (MMAE, a tubulin inhibitor) connected through the SuO-Val-Cit-PAB peptide.
T17938 Endo-BCN-PEG4-Val-Cit-PAB-MMAE Others
Endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable four-unit polyethylene glycol (PEG) linker, specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1].
T18250 MAL-di-EG-Val-Cit-PAB-MMAE Others
MAL-di-EG-Val-Cit-PAB-MMAE comprises the linker MAL-di-EG-Val-Cit-PAB and the potent tubulin inhibitor MMAE, which are essential components of antibody-drug conjugates (ADCs).
T17435 Amino-PEG4-Val-Cit-PAB-MMAE Others
Amino-PEG4-Val-Cit-PAB-MMAE is a cleavable tetraethylene glycol (4 unit PEG) antibody-drug conjugate (ADC) linker employed in the synthesis of ADCs[1].
T18299 Mal-PEG8-Val-Cit-PAB-MMAE Others
Mal-PEG8-Val-Cit-PAB-MMAE is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
T67428 MDPR-Val-Cit-PAB-MMAE
mDPR-Val-Cit-PAB-MMAE consists the ADCs linker (mDPR-Val-Cit-PAB) and potent tubulin inhibitor (MMAE), mDPR-Val-Cit-PAB-MMAE is an antibody drug conjugate.
T81361 PSMA-Val-Cit-PAB-MMAE
PSMA-Val-Cit-PAB-MMAE is a novel PSMA-targeted small-molecule conjugate leveraging monomethyl auristatin E (MMAE) for prostate cancer chemotherapy.
T77866 OH-Glu-Val-Cit-PAB-MMAE
OH-Glu-Val-Cit-PAB-MMAE is a compound comprising a cleavable ADC linker (OH-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE), utilized in the synthesis of antibody-drug conjugates (ADCs) [1].
T77885 (Aminooxy)acetamide-Val-Cit-PAB-MMAE
(Aminooxy)acetamide-Val-Cit-PAB-MMAE (MMAE 5) serves as an intermediate for synthesizing drug-linker conjugates in antibody-drug conjugates (ADCs). This compound is first conjugated to a polyamide through oxime bond form...
T18321 Mc-Val-Cit-PAB-Cl Others
Mc-Val-Cit-PAB-Cl, a cleavable ADC linker, is utilized in the conjugation of MMAE and antibodies to produce compounds such as antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE), which demonstrate cytotoxicity with IC5...
T77839 Bi-Mc-VC-PAB-MMAE
Bi-Mc-VC-PAB-MMAE is an agent-linker conjugate for antibody-drug conjugates (ADCs), featuring the linker (Fmoc-Val-Cit-PAB) and the potent tubulin inhibitor (MMAE).
T80884 Val-Cit-amide-Ph-Maytansine
Val-Cit-PAB-MMAE is a molecular entity designed to function as an antibody-drug conjugate (ADC) or as a component of bispecific antigen-binding molecules, specifically targeting the hepatocyte growth factor receptor know...
T77892 Mal-PEG8-Val-Cit-PAB-MMAF
Mal-PEG8-Val-Cit-PAB-MMAF is a drug-linker conjugate utilized for antibody-drug conjugates (ADCs), comprising a cleavable linker system and the potent tubulin inhibitor monomethyl auristatin F (MMAF), aimed at targeted c...
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