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Cat No. | Product Name | Synonyms | Targets |
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T62095 | TRK-IN-19 | ||
TRK-IN-19 (Compound I-10 ) is a potent inhibitor of TRK with IC50 values of 1.1 nM for TRKA and 5.3 nM for TRKAG595R. TRK-IN-19 has shown potential research value in cancer disease. | |||
T61443 | Trk-IN-7 | ||
Trk-IN-7 (compound I-6) is a highly potent inhibitor of TRK, exhibiting IC50 values ranging from 0.25-10 nM for TRKA, TRKB, and TRKC, respectively. In addition, Trk-IN-7 demonstrates notable inhibition against EML4-ALK (... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00774 | TrkA Protein, Human, Recombinant (aa 33-417, His) | Human | HEK293 Cells |
TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces receptor autophosphorylation and activation of intracellular signa... |