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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T18364 | Tesirine | MP-PEG8-VA-PABC-PBD Dimer | Others |
MP-PEG8-VA-PABC-PBD Dimer is a drug-linker conjugates for ADC which is used in the treatment of several cancers. PBD Dimer is a DNA alkylating which inhibits DNA replication[1]. | |||
T76854 | Loncastuximab tesirine | ||
Loncastuximab tesirine, a human cluster of differentiation 19 (CD19)-directed antibody-drug conjugate (ADC), binds to CD19 on the cell membrane, facilitating rapid internalization and inducing cell apoptosis. This mechan... | |||
T9227 | Val-Ala-PAB | Others | |
Val-Ala-PAB is a building block in the synthesis of Tesirine (a.k.a. SG3249), a clinical antibody-drug conjugate pyrrolobenzodiazepine dimer payload. Reagent in the preparation of pyrrolobenzodiazepine dimers and their a... | |||
T77822 | Mal-PEG8-Val-Ala-PABC | ||
Mal-PEG8-Val-Ala-PABC is a cleavable linker utilized in the synthesis of Tesirine, an agent-linker conjugate for Antibody-Drug Conjugates (ADC) [1]. | |||
T77813 | SG3199-Val-Ala-PAB | ||
SG3199-Val-Ala-PAB is an intermediate in the synthesis of Tesirine, a conjugate of agent-linker for antibody-drug conjugates (ADCs), utilized in the research of various cancers [1]. | |||
T77849 | Val-Ala-PABC-Exatecan | ||
Val-Ala-PABC-Exatecan is a Drug-Linker Conjugate for Antibody-Drug Conjugate (ADC) synthesis, comprising a cleavable Tesirine linker (Val-Ala-PABC) and the topoisomerase I inhibitor Exatecan. It is utilized in the constr... |