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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6253 | Talazoparib | LT-673,BMN-673 | PARP |
Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM). | |||
T16979 | Talazoparib tosylate | BMN 673ts | PARP |
Talazoparib tosylate is a novel and potent PARP1/2 (n IC50: 0.57 nM for PARP1). | |||
T10564 | (8R,9S)-Talazoparib | (8R,9S)-BMN-673 | Others |
(8R,9S)-Talazoparib is Talazoparib enantiomer , less active than Talazoparib on the inhibition of PARP1 (IC50: 144 nM). | |||
T79667 | YCH1899 | PARP | |
YCH1899, an orally active PARP inhibitor, demonstrates potent inhibition of PARP1/2 with an IC50 of less than 0.001 nM. It shows marked antiproliferative efficacy against Olaparib-resistant (Capan-1/OP) and Talazoparib-r... |