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Search Results for " twik-1/trek-1-in-1 "

4

Compounds

Cat No. Product Name Synonyms Targets
T78868 TWIK-1/TREK-1-IN-1 Potassium Channel
Compound 2a, identified as TWIK-1/TREK-1-IN-1, acts as an inhibitor of the TREK-1, a two-pore domain potassium channel (K2p) that forms TREK-1 homodimers and TWIK-1/TREK-1 heterodimers, both significant for its role as a...
T78870 TWIK-1/TREK-1-IN-3 Potassium Channel
TWIK-1/TREK-1-IN-3 is a selective and potent inhibitor of potassium channel TREK-1, inhibiting TREK-1 homodimers and TWIK-1/TREK-1 heterodimers containing two-pore-domain potassium (K2p) channels.TWIK-1/TREK-1-IN-3 exhib...
T78869 TWIK-1/TREK-1-IN-2 Potassium Channel
TWIK-1/TREK-1-IN-2 (Compound 2g) serves as an inhibitor of both TWIK-1 and TREK-1, targeting the TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC50 values of 10.13 μM and 15.5 μM, respectively. Additionally, it exh...
T83962 C 101248
C 101248 is a selective and potent inhibitor targeting both mouse and human tandem pore domain halothane-inhibited K+ channel 1 (THIK-1, IC50= 50 nM), without affecting the K2P family members (TREK-1, TWIK-2) and Kv2.1. ...
TargetMol