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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8222 | Selpercatinib | LOXO-292 | c-RET |
Selpercatinib (LOXO-292) is a tyrosine kinase inhibitor with antineoplastic properties(IC50 of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M) , and RET (G810R), respectively) | |||
T35384 | TPX-0046 | c-RET , Src | |
TPX-0046 is a RET inhibitor designed to overcome resistance to Selpercatinib and Pralsetinib. |