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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T38889 | Thailanstatin A | ||
Thailanstatin A is an ultra-potent inhibitor of eukaryotic RNA splicing (IC50 =650 nM). Thailanstatin A inhibits multiple cancer cell lines via non-covalent binding to the SF3b subunit of the U2 snRNA subcomplex of the s... | |||
T62267 | 18-Deoxyherboxidiene | ||
18-Deoxyherboxidiene (RQN-18690A) is a potent inhibitor of angiogenesis. 18-Deoxyherboxidiene selectively acts on SF3b, a subcomplex of the U2 small nuclear ribonucleoprotein (snRNP) in the spliceosome. 18-Deoxyherboxidi... | |||
T36749 | Herboxidiene | ||
Herboxidiene is a polyketide originally isolated from S. chromofuscus that has diverse biological activities.[1],[2,][3],[4],[5] It inhibits growth of HeLa S3, SK-MEL-2, PC3, A549, and EBC-1 cells with GI50 values rangin... |