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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12853 | SBI-477 | Others | |
SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factor MondoA. SBI-477 coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal... | |||
T60033 | SBI993 | Others | |
SBI993 is an analog of SBI-477 and can be used as a biomarker to confirm the expected action of MondoA target gene expression in vivo. SBI993 reduces muscle TAG levels and hepatic steatosis. | |||
T73409 | SBI-993 | ||
SBI-993, an analog of SBI-477, exhibits enhanced potency and possesses pharmacokinetic properties conducive to in vivo bioavailability. It promotes insulin signaling through the inhibition of the transcription factor Mon... |