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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6636 | Refametinib | BAY 86-97661,BAY 869766,RDEA119 | MEK |
Refametinib (RDEA119) (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 (IC50: 19/47 nM). | |||
T12697 | Refametinib R enantiomer | RDEA119 R enantiomer,Refametinib R enantiomer,BAY 869766 R enantiomer | MEK |
Refametinib R enantiomer (RDEA119 R enantiomer) is an MEK inhibitor with an EC50 of 2.0-15 nM.Refametinib (R enantiomer) has anticancer activity and can be used in cancer research. |