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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T61169 | PqsR-IN-1 | ||
PqsR-IN-1 (Compound 18) is a potent inhibitor of PqsR, which is a transcriptional regulator involved in the quorum sensing mechanism of Pseudomonas aeruginosa. This compound effectively reduces the production of pyocyani... | |||
T62015 | PqsR/LasR-IN-1 | ||
PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of LasR and PqsR systems in P. aeruginosa. PqsR/LasR-IN-1 is also a inhibitor of hERG (IC50= 6.77 μM). | |||
T60770 | PqsR/LasR-IN-3 | ||
PqsR/LasR-IN-3 (Compound 7a) inhibits hERG with the IC 50 of 109.01 μM which is also a PqsR and LasR systems inhibitor in P. aeruginosa [1]. | |||
T61353 | PqsR-IN-2 | ||
PqsR-IN-2 (Compound 19) is a highly potent inhibitor of PqsR, the transcriptional regulator responsible for quorum sensing in Pseudomonas aeruginosa. It effectively suppresses pyocyanin production without causing signifi... | |||
T14043 | 4-(tert-Butyl)-benzhydroxamic Acid | Others | |
4-(tert-Butyl)-benzhydroxamic Acid is a PqsR antagonist with IC50s of 12.5 μM and 23.6 μM for E. coli and P. aeruginosa, respectively, and it reduces the production of the virulence factor pyocyanin in P. aeruginosa with... | |||
T60249 | RhlR antagonist 1 | ||
RhlR antagonist 1 is a highly effective antagonist of the RhlR protein, showing an IC50 value of 26 μM. It exhibits selective antagonistic activity against RhlR, with minimal effect on LasR and PqsR. RhlR antagonist 1 st... |