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Search Results for " pgrn "

Targets

5

Compounds

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T9044 SORT-PGRN interaction inhibitor 1 Neurotensin Receptor
SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM).
T81126 SORT-PGRN interaction inhibitor 2
SORT-PGRN Interaction Inhibitor 2 is a compound that downregulates SORT1 protein expression and enhances extracellular progranulin (PGRN) secretion in various mammalian cell lines, and is utilized in the study of neurolo...
T79106 SORT-PGRN interaction inhibitor 3 Neurotensin Receptor
SORT-PGRN Interaction Inhibitor 3 (Compound 13), with an IC50 value of 0.17 μM, acts as an inhibitor of the SORT-PGRN interaction, and is utilized in the study of neurodegenerative diseases [1].
T77053 Latozinemab GSK-4527223,AL-001 Neurotensin Receptor
Latozinemab (AL001) is a potent and selective recombinant humanized monoclonal antibody against Sortilin.Latozinemab has a high affinity for Sortilin and interrupts the interaction between the granule protein precursor (...
T79105 BVFP Neurotensin Receptor
BVFP exhibits affinity for the PGRN 588–593 peptide through binding with a dissociation constant (Kd) of 20 μM and is capable of disrupting the interaction between PGRN and SORT1. Moreover, BVFP inhibits the SORT1-mediat...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00978 Progranulin Protein, Human, Recombinant (His) Human HEK293 Cells
Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1.
TMPY-01435 Progranulin Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Progranulin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63 kDa and the accession number is P28798.
TargetMol