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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12675L | PT2399 | HIF/HIF Prolyl-Hydroxylase , HIF | |
PT2399 shows effective antitumor activity in vivo. PT2399 is an effective and selective HIF-2α antagonist, which directly binds to the HIF-2α PAS B domain (IC50: 6 nM). | |||
T12675 | (Rac)-PT2399 | HIF | |
(Rac)-PT2399 is a potent and specific inhibitor of hypoxia-inducible factor 2a (HIF-2α)(IC50 of 0.01 μM). |