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Search Results for " prmt5-in-2 "

4

Compounds

Cat No. Product Name Synonyms Targets
T16577 PRMT5-IN-2 Histone Methyltransferase
PRMT5-IN-2 is an inhibitor of protein arginine methyltransferase 5.
T79274 PRMT5-IN-31 Histone Methyltransferase
PRMT5-IN-31 (Compound 3m), a selective PRMT5 inhibitor (IC50: 0.31 μM), increases hnRNP E1 protein levels by occupying the substrate site of PRMT5 and establishing key interactions with amino acid residues. It exhibits a...
T36630 MRTX9768 hydrochloride
MRTX9768 hydrochloride is a potent, orally active PRMT5 inhibitor. MRTX9768 hydrochloride is a synthetic lethal-based inhibitor binding the PRMT5-MTA complex[1]. MRTX9768 inhibits SDMA and cell proliferation in HCT116 MT...
T79275 Antiproliferative agent-25 Histone Methyltransferase
Antiproliferative Agent-25 (Compound 3s4) is a selective PRMT5 inhibitor displaying an IC50 of 0.11 μM. It elevates hnRNP E1 protein levels and forms hydrogen bond interactions with SAM and the E444 residue of PRMT5. Thi...
TargetMol