4
1
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60169 | BLU0588 | Others | |
BLU0588 is a selective PRKACA inhibitor. BLU0588 inhibits PRKACA catalytic activity with a half-maximal inhibitory concentration (IC50) of 1 nM. | |||
T60170 | BLU2864 | Others | |
BLU2864 is an orally active, highly selective, ATP-competitive PRKACA inhibitor with IC 50 of 0.3 nM. BLU2864 exhibits anti-tumor activity. BLU2864 has potential to be used in cancer and polycystic kidney disease researc... | |||
T63041 | DS01080522 | ||
DS01080522 is an inhibitor of PRKACA. DS01080522 inhibited PRKACA kinase activity (IC50.0.8 nM) and CREB phosphorylation (IC50.66 nM). DS0108052 can be used to study cancer. | |||
T62676 | DS89002333 | ||
DS89002333 is a potent, orally active PRKACA inhibitor (IC50: 0.3 nM).DS89002333 has shown good antitumor effects in a patient-derived xenograft model of FL-HCC expressing a DNAJB1-PRKACA fusion gene.DS89002333 can be us... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00677 | PKA/PRKACA Protein, Canine, Recombinant (His) | Canine | E. coli |
The cAMP-dependent protein kinase PKA is a well-characterized member of the serine-threonine protein AGC kinase family and is the effector kinase of cAMP signaling. As such, PKA is involved in the control of a wide varie... |