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Search Results for " pgrn "

Targets

5

Compounds

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T9044 SORT-PGRN interaction inhibitor 1 Neurotensin Receptor
SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM).
T81126 SORT-PGRN interaction inhibitor 2
SORT-PGRN Interaction Inhibitor 2 is a compound that downregulates SORT1 protein expression and enhances extracellular progranulin (PGRN) secretion in various mammalian cell lines, and is utilized in the study of neurolo...
T79106 SORT-PGRN interaction inhibitor 3 Neurotensin Receptor
SORT-PGRN Interaction Inhibitor 3 (Compound 13), with an IC50 value of 0.17 μM, acts as an inhibitor of the SORT-PGRN interaction, and is utilized in the study of neurodegenerative diseases [1].
T77053 Latozinemab GSK-4527223,AL-001 Neurotensin Receptor
Latozinemab (AL001) is a potent and selective recombinant humanized monoclonal antibody against Sortilin.Latozinemab has a high affinity for Sortilin and interrupts the interaction between the granule protein precursor (...
T79105 BVFP Neurotensin Receptor
BVFP exhibits affinity for the PGRN 588–593 peptide through binding with a dissociation constant (Kd) of 20 μM and is capable of disrupting the interaction between PGRN and SORT1. Moreover, BVFP inhibits the SORT1-mediat...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00978 Progranulin Protein, Human, Recombinant (His) Human HEK293
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The precursor protein, progranulin, ...
TMPY-01435 Progranulin Protein, Mouse, Recombinant (His) Mouse HEK293
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The precursor protein, progranulin, ...
TargetMol