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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2041 | PD153035 | NSC 669364,SU-5271,ZM 252868,AG1517 | EGFR |
PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in cell-free assays); little inhibitory against FGFR, PGDFR, InsR, CSF-1 and Src. | |||
T1761 | PD153035 hydrochloride | ZM 252868 HCl,AG 1517,Tyrphostin AG 1517,SU 5271,PD153035 HCl,ZM 252868 | EGFR |
PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR (Ki: 5.2 pM, IC50: 29 pM); few influence against FGFR, PGDFR, InsR, CSF-1, and Src. | |||
T69055 | PD153035 nitrate | ||
PD153035 is a ATP-competitive EGFR inhibitor with an IC50 and Ki of 25 and 6 pM. PD153035 effectively blocks the enhancement of mitogenesis, induction of early gene expression, and oncogenic transformation that occur in ... | |||
T69985 | Lifirafenib HCl | ||
Lifirafenib, also known as Beigene-283, is a Novel potent and selective RAF Kinase and EGFR inhibitor. BGB-283-displays Potent Antitumor Activity in B-RAF Mutated Colorectal Cancers. In vitro, BGB-283 potently inhibits ... | |||
T3558 | EBE-A22 | PD153035 Analog 63 | EGFR |
EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive. |