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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16422 | P110δ-IN-1 | PWT-143 | PI3K |
P110δ-IN-1 (PWT-143) is an effective and selective inhibitor of P110δ (IC50: 8.4 nM). | |||
T78568 | PI3Kδ-IN-15 | PI3K | |
PI3Kδ-IN-15 (compound 6b) is a potent and selective inhibitor of PI3Kδ, exhibiting an IC50 of 0.5 nM for p110δ and demonstrating over 30-fold selectivity compared to PI3K isoforms γ, β, and α [1]. | |||
T14191 | Alpelisib hydrochloride | BYL-719 hydrochloride | Others |
Alpelisib hydrochloride (BYL-719 hydrochloride) exhibits anticancer properties[1][2]. As a potent, selective PI3Kα inhibitor with high oral bioavailability, it demonstrates IC50 values of 5 nM for p110α, 250 nM for p110γ... |