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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T62422 | Nav1.8-IN-2 | ||
Nav1.8-IN-2 (compound 35A) is a potent inhibitor of Nav1.8 (IC50: 0.4 nM). Nav1.8-IN-2 can be used in studies of pain disorders, cough, acute and chronic pruritus. | |||
T8579 | Nav1.8-IN-1 | 5-(4-Chlorophenyl)-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]pyridine-3-carboxamide,CHEMBL1270208 | Sodium Channel |
Nav1.8-IN-1 (CHEMBL1270208) is an inhibitor of human NaV1.8 | |||
T78955 | Analgesic agent-2 | Sodium Channel | |
Analgesic Agent-2, a selective orally active inhibitor of the NaV1.8 channel, demonstrates an IC50 of 50.18 nM in HEK293 cells that stably express the human NaV1.8 channel, indicating its potential for analgesic activity... | |||
T37093 | 4,9-Anhydrotetrodotoxin | 4,9-Anhydrotetrodotoxin,4,9-anhydro-TTX | |
4,9-Anhydrotetrodotoxin (4,9-anhydro-TTX) is a derivative of TTX that selectively blocks inward sodium current through Nav1.6 voltage-activated sodium channels (IC50 = 7.8 nM in Xenopus oocytes). [1][2][3] It demonstrate... |