nmt — TargetMol Chemicals

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Search Results for " nmt "

Compounds

Cat No.	Product Name	Synonyms	Targets
T67919	NMT-IN-1		Others
	NMT-IN-1 is a potent inhibitor of N-nutyltransferase (NMT), with IC50 of 31μM for TbNMT and 66μM for hNMT. NMT-IN-1 is a potential compound for the treatment of African trypanosomiasis.		Others
T27135	DDD85646	DDD 85646,DDD-85646	Parasite
	DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.		Parasite
T8760	NNMTi	5-Amino-1-methylquinolinium	Others
	NNMTi (5-Amino-1-methylquinolinium) is a substrate site-targeting, selective nicotinamide N-methyltransferase (NNMT) inhibitor (IC50 = 1.2 μM; 50 μM SAM, 100 μM NCA) that reduces 3T3-L1 lipogenesis (EC50 = 30μM) and adip...		Others
T38437	NMTCA	N-Nitroso-2-methylthiazolidine4-carboxylicacid,NMTPRO,N-nitrosomethylthioproline
	NMTCA (NMTPRO) is a sulfur-containing N-nitrosamino acid utilized as an endogenous nitrosation indicator in gas chromatography-thermal energy analysis.
T63859	DNMT3A-IN-1
	DNMT3A-IN-1 is a selective and potent DNMT3A inhibitor. DNMT3A-IN-1 exhibits inhibitory activity against DNMT3A with a KI ranging from 9.16-18.85 μM (AdoMet) and 11.37-23.34 μM (poly dI-dC).
T81661	NNMT-IN-4
	NNMT-IN-4 (compound 38) is a selective, uncompetitive inhibitor of nicotinamide N-methyltransferase (NNMT) with in vitro biochemical and cell-based assay IC50 values of 42 nM and 38 nM, respectively. It demonstrates favo...
T63493	NNMT-IN-2
	NNMT-IN-2 is a very potent inhibitor of NNMT (IC50: 3.7 nM).
T81432	PNMT-IN-1
	PNMT-IN-1 (inhibitor 4) is a selective second generation inhibitor [1] of phenylethanolamine N-methyltransferase (PNMT), exhibiting a Ki value of 1.2 nM and an IC50 value of 81 nM. Additionally, it disrupts the activity ...
T64189	NNMT-IN-3
	NNMT-IN-3 (compound 14) is a potent and selective inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 values of 1.1 nM and 0.4 μM in cell-free and cell-based assays, respectively. nNMT-IN-3 can be used in stud...
T23477	Tris(dibenzylideneacetone)dipalladium	Tris DBA	Others
	tris(dibenzylideneacetone)dipalladium (Tris DBA) is a N-myristoyltransferase-1 (NMT-1) inhibitor		Others
T63788	PCLX-001		Others
	PCLX-001 is a small-molecule compound that acts as an orally active inhibitor of N-myristoyltransferase (NMT), specifically targeting NMT1 and NMT2 with IC50 values of 5 nM and 8 nM, respectively. This compound demonstra...		Others
T27831	Lifibrate
	Lifibrate is an inhibitor of cholinephosphotransferase (CPT), phosphatidyl-N,N-dimethylethanolamine N-methyltransferase (PDE-NMT), and phosphatidyl-N-methylethanolamine N-methyltransferase (PME-NMT).
T28701	SC-58272	SC58272
	SC-58272 is an inhibitor of N-myristoyltransferase (Nmt), a target for anti-fungal and anti-viral therapy.
T27127	DCAT Maleate	DCAT
	DCAT Maleate is an inhibitor of N-methyl transferases (NMT). DCAT Maleate methylate non-methylated pre-neurotoxins to prevent the formation of Parkinson's syndrome neurotoxins.
T68562	FTR-1335
	FTR1335 is a CaNMT inhibitor (IC50 = 0.49 nM) with good fungal selectivity. CaNMT inhibitors are fungicidal and show antifungal activity against Candida (especially fluconazole-resistant strains). They function by inhibi...