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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T72224 | NK1 receptor antagonist 2 | Others | |
NK1 Receptor Antagonist 2, a compound targeting the NK1 receptor, holds potential for tinnitus and hearing loss research. | |||
T3724 | Rolapitant hydrochloride | Rolapitant HCl | Neurokinin receptor |
Rolapitant (SCH619734) hydrochloride is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant hydrochloride (Rolapitant HCl) does not interact with CY... | |||
T84898 | CP 122721 hydrochloride | Others | |
CP 122721 hydrochloride is a potent and selective non-peptide (nonpeptide) neurokinin NK1 antagonist, demonstrating a pIC50 of 9.8 against the human NK1 receptor in IM-9 cells. It exhibits anxiolytic and antidepressant-l... | |||
T75837 | Spantide I TFA | ||
Spantide I TFA, a selective NK1 receptor antagonist and a substance P analog, exhibits K(i) values of 230 nM for NK1 and 8150 nM for NK2 receptors, respectively. It offers a method to decrease type 1 while increasing typ... | |||
T75881 | GR 64349 TFA | ||
GR 64349 is a potent and highly selective NK2 receptor peptide antagonist, demonstrating an EC50 of 3.7 nM in rat colon. It exhibits over 1000-fold selectivity against NK1 receptors and over 300-fold selectivity against ... | |||
T75880 | GR 94800 TFA | ||
GR 94800 TFA is a potent, selective antagonist of the NK 2 receptor peptide, demonstrating pK B values of 9.6 for NK 2, 6.4 for NK 1, and 6.0 for NK 3 receptors, respectively [1] [2]. |