4
3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6789 | BMS582949 | BMS 582949,PS540446,BMS-582949 | p38 MAPK |
BMS-582949 is a potent and selective p38 mitogen-activated protein kinase (p38 MAPK) inhibitor with IC50 of 13 nM, inhibiting both p38 kinase activity and activation of p38. | |||
T27345 | FMS586 | FMS-586,FMS 586 | |
FMS586 is a selective antagonist of neuropeptide Y Y5 receptor with oral activity. | |||
T74299 | MS5033 | ||
MS5033 is a potent proteolysis-targeting chimera (PROTAC) that effectively degrades AKT (also known as protein kinase B), exhibiting a half-maximal degradation concentration (DC50) of 430 nM in PC3 cells [1]. | |||
T64223 | RMS5 | ||
RMS5 is a hambanine analogue and a potent P-glycoprotein (P-gp) inhibitor.RMS5 has significant anti-proliferative and cytotoxic effects on cancer cells.RMS5 slightly reduces the expression of the anti-apoptotic Bcl-2 fam... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01459 | TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) | Human | HEK293 Cells |
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P19438-1. | |||
TMPK-00564 | TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of... | |||
TMPY-05475 | TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is P19438-1. |