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Search Results for " mrtx1257 "

1

Compounds

Cat No. Product Name Synonyms Targets
T16143 MRTX-1257 Ras
MRTX-1257 is a selective, irreversible, and covalent inhibitor of KRAS G12C. It has an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells. MRTX1257 demonstrated 31% bioavailability in the mouse, with fre...
TargetMol