1
2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T72624 | Kallikrein 5-IN-2 | ||
Kallikrein 5-IN-2 is a potent inhibitor of Kallikrein KLK5, exhibiting selectivity with a pIC50 value of 7.1. By inhibiting KLK5, it has the potential to normalize epidermal shedding, thereby reducing associated inflamma... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01405 | Kallikrein 5/KLK5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Kallikrein 5/KLK5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40 KDa and the accession number is Q9Y337. | |||
TMPK-01158 | Kallikrein 5/KLK5 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
The inhibition of kallikrein 5 (KLK5) has been identified as a potential strategy for treatment of the genetic skin disorder Netherton syndrome, in which loss-of-function mutations in the SPINK5 gene lead to down-regulat... |