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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T27723 | KDM5-C49 | KDM5C49 | |
KDM5-C49 is a potent and selective inhibitor of KDM5, which regulates cell proliferation and stem cell self-renewal and differentiation. | |||
T27723L | KDM5-C49 HCl | KDM5-C49 HCl(1596348-16-1 Free base),KDOAM-20 hydrochloride | Histone Demethylase |
KDM5-C49 HCl (KDOAM-20 hydrochloride) is a potent and selective inhibitor of KDM5 demethylase. KDM5-C49 HCL(1596348-16-1 Free base) is a candidate compound for the treatment of cancer. | |||
T15648 | KDM5-C70 | Histone Demethylase | |
KDM5-C70 is an ethyl ester derivative of KDM5-C49. KDM5-C70 is an effective, cell-permeable, and pan-KDM5 histone demethylase inhibitor. KDM5-C70 has an antiproliferative effect in myeloma cells, inducing a genome-wide e... | |||
T73849 | KDM5-C49 hydrochloride | ||
KDM5-C49 (KDOAM-20) hydrochloride is a potent, selective inhibitor of the KDM5 family of demethylases, demonstrating IC50 values of 40 nM for KDM5A, 160 nM for KDM5B, and 100 nM for KDM5C, respectively. This compound is ... |