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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11706 | Londamocitinib | AZD4604 | JAK |
Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity. | |||
T35900 | JAK2-IN-7 | JAK2-IN-7 | JAK |
JAK2-IN-7, a selective inhibitor targeting Janus Kinase 2 (JAK2), exhibits inhibitory concentrations (IC50) of 3 nM for JAK2, 11.7 nM for SET-2 cells, and 41 nM for Ba/F3 V617F cells, indicative of its potency and select... | |||
T63581 | JAK-IN-20 | ||
JAK-IN-20 is a potent, orally active, broad-based JAK inhibitor, capable of acting on JAK1 (IC50: 7 nM), JAK2 (IC50: 5 nM), and JAK3 (IC50: 14 nM).JAK-IN-20 has excellent pharmacokinetic and anti-inflammatory activity in... |