hcv-in-3 — TargetMol Chemicals

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Search Results for " hcv-in-3 "

Compounds

Cat No.	Product Name	Synonyms	Targets
T11540	HCV-IN-3		Others
	HCV-IN-3 is a hepatitis C virus (HCV) NS3/4a protein inhibitor (IC50: 20 μM; Kd: 29 μM).		Others
T6229	Daclatasvir	Daklinza,EBP 883,BMS-790052	HCV Protease
	Daclatasvir (EBP 883) (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. Phase 3.		HCV Protease
T3226	Paritaprevir	ABT-450,Veruprevir	HCV Protease
	Paritaprevir (ABT-450) is an orally bioavailable, synthetic acylsulfonamide inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural protein 3 and 4A (NS3/NS4A), with potential activity again...		HCV Protease
T11548	HCV-IN-7		Others
	HCV-IN-7 is an orally active and potent pan-genotypic HCV NS5A inhibitor (IC50s: 3-47 pM). It shows a superior pan-genotypic profile and a good pharmacokinetic profile coupled with a favorable liver uptake.		Others
T11548L	HCV-IN-7 hydrochloride		Others
	HCV-IN-7 hydrochloride is an orally active and potent pan-genotypic HCV NS5A inhibitor (IC50s: 3-47 pM). It shows a superior pan-genotypic profile and a good pharmacokinetic profile coupled with a favorable liver uptake.		Others
T10986	DDX3-IN-1		Others
	DDX3-IN-1 is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50 of 50 and 36 μM for HIV and HCV, respectively. Antiviral activity.		Others
TP1468	HCV-IN-4
	HCV-IN-4, a potent and orally active inhibitor of HCV NS5A, demonstrates significant efficacy against genotypes GT1a, GT2b, GT3a, and the GT1a mutations Y93H and L31V. Its half-maximal effective concentrations (EC90s) ar...
T68235	Beclabuvir HCl
	Beclabuvir, also known as BMS-791325, is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase. BMS-791325 inhibits recombinant NS5B proteins from HCV genotyp...
T19627	Ciluprevir	BILN 2061ZW,BILN 2061,BILN-2061ZW,BILN-2061,BILN2061ZW,BILN2061
	Ciluprevir is an effective and selective HCV NS3 protease inhibitor with proven antiviral effect in humans. Ciluprevir may be an antiviral agent for individuals infected with non-genotype-1 HCV. In vitro sensitivity stud...
T35533	6-Hydroxypyridin-3-ylboronic Acid
	6-Hydroxypyridin-3-ylboronic acid is a heterocyclic building block.1,2It has been used in the synthesis of non-nucleoside inhibitors of hepatitis C virus (HCV) RNA-dependent RNA polymerase nonstructural protein 5B (NS5B)...
T74301	PSI-353661
	PSI-353661 (GS-558093), a purine nucleotide NS5B polymerase inhibitor, is effective against HCV infection, displaying EC90 values of 8 nM and 11 nM for wild-type and S282T resistant HCV replicons, respectively. It is cap...
T73223	NS5A-IN-3		HCV Protease
	NS5A-IN-3 (Compound 15) serves as a potent NS5A inhibitor, displaying exceptionally high efficacy against HCV genotype 1b, enhanced activity towards genotype 3a (GT 3a), and substantial metabolic stability. It also demon...		HCV Protease
T38297	Ribavirin-13C5	Ribavirin-13C5
	Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to a...