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Search Results for " gne987 "

2

Compounds

Cat No. Product Name Synonyms Targets
T11441 GNE-987 Epigenetic Reader Domain
GNE-987 is a highly active chimeric BET degrader. GNE-987 binds equipotently to the BD1 and BD2 bromodomains of BRD4 with low nanomolar affinities (IC50: 4.7 and 4.4 nM, respectively). GNE-987 exhibits picomolar cell BRD...
T12798 (S)-GNE-987 Epigenetic Reader Domain
(S)-GNE-987 binds to the BRD4 BD1(IC50=4 nM) and BD2 (3.9 nM) bromodomains and can be used to design PROTAC-Antibody Conjugate (PAC).
TargetMol