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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T64059 | G12Si-5 | ||
G12Si-5 is a covalent inhibitor of the K-RasG12S mutant with a Ki value of 26 μM. G12Si-5 binds to the S-IIP structural domain and inhibits oncogenic signalling. g12Si-5 reduces ERK phosphorylation levels in KRAS G12S mu... |