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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T40031 | Thalidomide-O-C6-NH2 hydrochloride | 4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride | E3 Ligase Ligand-Linker Conjugate |
Thalidomide-O-C6-NH2 hydrochloride (4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride) is a synthesized E3 ligase ligand-linker conjugate. | |||
T40251 | DTAGV-1 TFA | ||
dTAGV-1 TFA is a highly effective and specific compound that targets mutant FKBP12 F36V fusion proteins for degradation. It possesses potent activity in inducing the degradation of the FKBP12 F36V -Nluc protein in living... | |||
T13549 | AP1867-3-(aminoethoxy) | Others | |
AP1867-3-(aminoethoxy) is a synthetic ligand for FKBP and can be used in the synthesis of PROTAC FKBP12 F36V degrader. | |||
T74556 | DTAG-47 | ||
dTAG-47, a heterobifunctional molecule, specifically targets the mutant FKBP12 (FKBP12 F36V), which functions as a degradation tag (dTAG) when fused to a protein of interest. This compound is utilized in the study of bas... | |||
T74412 | DTAGV-1-NEG TFA | ||
dTAGV-1-NEG TFA, a diastereomer, serves as the heterobifunctional negative control for dTAGV-1. It acts specifically as an FKBP12 F36V-selective degrader [1]. | |||
T36253 | DTAGV-1 | ||
Degrader targeting mutant FKBP12F36V fusion proteins. Comprises a ligand selective for F36V single-point mutated FKBP12, a linker and a von Hippel-Lindau (VHL)-binding ligand. Induces potent and selective degradation of ... |