4
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21653 | 1,4-DPCA | HIF/HIF Prolyl-Hydroxylase | |
1,4-DPCA is an inhibitor of prolyl-hydroxylase with an IC50 of 2.4 µM for collagen hydroxylation in human foreskin fibroblasts and 60 μM for factor inhibiting HIF (FIH). | |||
T1823 | IOX2 | IOX 2,JICL38 | HIF/HIF Prolyl-Hydroxylase |
IOX2 (IOX 2) is a selective inhibitor of the Hypoxia Inducible Factor (HIF) Prolyl-Hydroxylases (PHD); active in cells with the IC50 value of 21 nM for PHD2/ELGN-1 and no inhibition at FIH (20uM). | |||
T36796 | 1,4-DPCA ethyl ester | ||
1,4-DPCA ethyl ester, the ethyl ester derivative of 1,4-DPCA, acts as an inhibitor of the enzyme factor inhibiting HIF (FIH)[1]. | |||
T68507 | DM-NOFD | ||
DM-NOFD is a cell penetrant prodrug of NOFD, which is a potent and selective inhibitor of an asparaginyl hydroxylase FIH (factor-inhibiting HIF). |