3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2346 | Enasidenib | AG-221 | Dehydrogenase , Isocitrate Dehydrogenase (IDH) |
Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potential antineoplastic activity. | |||
T2346L | Enasidenib mesylate | AG221 mesylate,AG 221 mesylate,AG-221 mesylate | Dehydrogenase |
Enasidenib mesylate (AG-221 mesylate) is a potent and selective IDH2 mutase inhibitor that promotes differentiation of leukemia myeloid cells for the treatment of acute myeloid leukemia. | |||
T70315 | AGI-16903 | ||
AGI-16903 is a metabolite of enasidenib -- an isocitrate dehydrogenase-2 inhibitor that has been shown to inhibit human nucleoside transporters and uptake of azacitidine in oocytes. |