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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11500L | GSK3368715 dihydrochloride | EPZ019997 dihydrochloride,GSK3368715 2HCl,EPZ019997 2HCl | Histone Methyltransferase |
GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active and potent inhibitor of type I protein arginine methyltransferases (PRMTs) with anticancer and antitumor activity, inhibiting PRMT1, PRMT3, PRMT4... | |||
T22342 | GSK3368715 3HCl | EPZ019997 3HCl,GSK3368715(EPZ019997) | Histone Methyltransferase |
GSK3368715, a potent inhibitor of type I protein arginine methyltransferases (PRMT), could inhibit PRMT1, 3, 4, 6 and 8 with Kiapp vaules ranging from 1.5 to 81 nM. | |||
T11500 | GSK3368715 | EPZ019997 | Histone Methyltransferase |
GSK3368715 is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50s: 3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRM... |